Does Semaglutide Make You Tired? Understanding Side Effects and Energy Levels

Dr. Farizani
December 4, 2024
Semaglutide has emerged as a groundbreaking medication for managing type 2 diabetes and achieving weight loss. By regulating blood sugar levels and reducing appetite, it helps individuals reach health milestones that may have felt out of reach. However, like any medication, semaglutide comes with potential side effects. One common question from those starting this treatment is: Does semaglutide make you tired?

If you’re feeling more tired than usual, you’re not alone. This blog will explore why fatigue can occur, how to manage it effectively, and what to expect as your body adjusts to the medication. Additionally, we’ll look at other side effects and highlight how semaglutide programs can support your overall health journey.

Why Does Semaglutide Make Some People Tired?

Fatigue is one of the side effects that some individuals experience when starting semaglutide. While it might feel discouraging, understanding the potential reasons behind this can provide clarity and reassurance.

Blood Sugar Regulation

Semaglutide is designed to lower and stabilize blood glucose levels. For individuals with type 2 diabetes, this effect is crucial for managing their condition. However, fluctuations in blood sugar levels during the initial stages of treatment can leave you feeling drained as your body adapts to the medication’s impact.

Decreased Caloric Intake

Semaglutide suppresses appetite, which can lead to a significant reduction in calorie consumption. While this is beneficial for weight loss, consuming fewer calories than your body needs can temporarily result in lower energy levels.

Metabolic Shifts

As semaglutide influences how your body processes food and stores energy, it initiates metabolic changes. These adjustments, while ultimately beneficial, can leave you feeling fatigued as your system gets used to functioning differently.

Medication Adjustment Period

Like many medications, semaglutide requires an adjustment phase. During this time, your body works to integrate the treatment into its systems, which can temporarily impact your energy levels.

How Does Semaglutide Affect Energy Levels Over Time?

The good news is that fatigue on semaglutide is typically temporary. Clinical studies and anecdotal reports suggest that most people begin to feel more energized after the initial adjustment phase. This can happen within a few weeks as your body learns to work with the medication rather than against it.

It’s also worth noting that semaglutide’s benefits, such as better blood sugar control, improved weight management, and reduced appetite, often lead to long-term boosts in energy and overall health.

How Do You Increase Energy on Semaglutide?

If you’re feeling tired on semaglutide, there are practical steps you can take to restore your energy and feel your best.

Stay Hydrated

Dehydration is a common culprit behind fatigue. Ensure you’re drinking enough water throughout the day, as proper hydration can improve your energy levels and your body’s ability to adapt to semaglutide.

Eat Nutrient-Dense Foods

Even if your appetite has decreased, it’s essential to focus on consuming high-quality, nutrient-rich meals. Incorporate whole grains, lean proteins, fruits, and vegetables to provide your body with the vitamins and minerals it needs for energy.

Maintain Light Physical Activity

While feeling tired might make exercise seem counterintuitive, engaging in gentle activities such as walking, stretching, or yoga can improve circulation, increase endorphins, and help combat fatigue.

Prioritize Restful Sleep

Quality sleep is vital, especially during the adjustment phase of semaglutide treatment. Create a bedtime routine, limit screen time before bed, and aim for 7-9 hours of uninterrupted rest each night.

Speak to Your Healthcare Provider

If your fatigue persists or worsens, don’t hesitate to consult your healthcare provider. They may adjust your dosage or provide additional recommendations to support your energy levels.

person using semaglutide

Other Common Side Effects of Semaglutide

In addition to fatigue, semaglutide has other potential side effects. Understanding what to expect can help you feel more prepared and confident in managing your treatment.

  • Nausea: Often reported during the first few weeks, nausea is one of the most common side effects. Eating smaller, more frequent meals can help alleviate this symptom.
  • Digestive Issues: Some individuals experience diarrhea or constipation as their gastrointestinal system adjusts to semaglutide.
  • Headaches: Temporary headaches can occur as a result of changes in blood sugar levels or dehydration.
  • Injection Site Reactions: Redness, swelling, or discomfort at the injection site are possible but usually mild.
  • Rare Thyroid Cancer Risks: Semaglutide carries a warning regarding thyroid tumors, though this risk is rare. Individuals with a history of thyroid cancer should discuss this with their provider before starting treatment.

It’s important to remember that these side effects are often mild and improve over time. For many, the benefits of semaglutide far outweigh these temporary challenges.

What to Expect as Your Body Adjusts

The adjustment period with semaglutide typically lasts a few weeks to a couple of months. During this time, your body works to regulate its responses to the medication. While fatigue, nausea, or other mild side effects may arise, they tend to diminish as your body becomes accustomed to the treatment.

For those using semaglutide for weight loss, it’s especially important to remain patient during this phase. The combination of reduced appetite, better blood sugar control, and metabolic changes will yield significant results in the long term, making the temporary discomforts worthwhile.

The Good News: Fatigue Often Improves Over Time

For most individuals, fatigue and other initial side effects subside as the body adjusts to semaglutide. With proper management, the long-term benefits of this treatment outweigh the temporary discomforts.

At Hillcroft Physicians, our semaglutide program is designed to support you every step of the way. From personalized treatment plans to ongoing monitoring by licensed medical providers, we ensure your experience is as comfortable and effective as possible. Our comprehensive program includes nutritional guidance, regular testing, and tailored care to help you achieve your weight management goals safely and sustainably.

Take the next step in your health journey with Hillcroft Physicians—where your goals are our priority. Visit our website today to learn more about our semaglutide program and how it can help you feel your best.

Dr. Farizani

Dr. Farizani created the medical and operational foundation of Hillcroft Physicians, PA., and expanded the clinic and its mission to become one of the largest small group practices in Houston. Dr. Farizani speaks English, Farsi, and Spanish.